HOMA-IR Calculator: Check Your Insulin Resistance in Seconds
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Enter your fasting glucose and fasting insulin below and you get your HOMA-IR instantly: below 1.0 is optimal insulin sensitivity, 1.0–1.9 is typical, 2.0–2.9 suggests early insulin resistance, and 2.9 or above indicates significant resistance. Both values must come from the same fasting blood draw (10–12 hours, water only).
Track it. Test it. Know for sure.
Log food, supplements, sleep and biomarkers by chatting with BioTrakk on Telegram, WhatsApp or the web — then let it find what actually moves your numbers.
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How is HOMA-IR calculated?
The formula comes from Matthews and colleagues (1985): HOMA-IR = fasting glucose (mg/dL) × fasting insulin (µIU/mL) ÷ 405. With glucose in mmol/L, divide by 22.5 instead. Worked example: glucose 95 mg/dL × insulin 8 µIU/mL = 760; 760 ÷ 405 = 1.88 — top of the typical band.
| HOMA-IR | Interpretation |
|---|---|
| Below 1.0 | Optimal insulin sensitivity |
| 1.0–1.9 | Typical — no clear resistance |
| 2.0–2.9 | Early insulin resistance |
| 2.9 and above | Significant insulin resistance |
Population data broadly agree with these bands: in the Spanish EPIRCE study, HOMA-IR cut-offs associated with metabolic syndrome fell between roughly 2 and 3.9 depending on age and sex.
Why does HOMA-IR matter more than fasting glucose alone?
Because insulin moves first. In the Whitehall II cohort, people who later developed type 2 diabetes had measurably reduced insulin sensitivity more than a decade before diagnosis, while their glucose stayed deceptively normal until the final 2–3 years. An analysis of the Kraft database found that just over half of people with completely normal glucose tolerance still showed hyperinsulinaemia. Glucose is the value your body defends; insulin is the price it pays — HOMA-IR captures the price.
For the full picture — optimal fasting insulin bands, test conditions, and the evidence-backed ways to lower it — read our fasting insulin guide.
What are the limits of HOMA-IR?
Three honest caveats. It mainly reflects fasting (hepatic) insulin resistance and can miss post-meal dysfunction. It is not valid if you inject insulin. And insulin assays are not fully standardized between manufacturers, so always compute it from results drawn at the same laboratory, and judge the trend across two or three tests rather than a single number. If your result sits above 2.9 — or above 2.0 alongside an expanding waist, high triglycerides or elevated uric acid — that is a conversation to have with your doctor, not a number to panic about alone.
Tracking an intervention? Log training, sleep and diet in BioTrakk, retest after 8–12 weeks, and run it as a structured n-of-1 experiment so the verdict comes from your data rather than your hopes.
Frequently asked questions
What is a good HOMA-IR score?
Below 1.0 is optimal, 1.0-1.9 is typical, 2.0-2.9 suggests early insulin resistance and 2.9 or above indicates significant resistance. Cut-offs vary somewhat by population and lab assay, so treat the bands as screening guidance, not a diagnosis.
What units does the HOMA-IR formula use?
Glucose in mg/dL with insulin in µIU/mL, divided by 405 — or glucose in mmol/L divided by 22.5. Insulin in pmol/L must first be converted to µIU/mL by dividing by 6.945. This calculator handles both glucose units.
Do I need to fast before testing for HOMA-IR?
Yes — a true 10-12 hour fast with water only, no morning workout before the draw, and a normal night of sleep. One short night can depress insulin sensitivity by roughly 20-25% and inflate your score.
Can HOMA-IR be too low?
A very low HOMA-IR in a healthy, lean person almost always just means excellent insulin sensitivity. Interpretation differs if you have diabetes with failing insulin production — HOMA-IR is not valid on injected insulin, and that situation belongs with your clinician.
Track it. Test it. Know for sure.
Log food, supplements, sleep and biomarkers by chatting with BioTrakk on Telegram, WhatsApp or the web — then let it find what actually moves your numbers.
Start freeFree on Telegram & Web. No app to install.
Sources
- Matthews DR et al. — Homeostasis model assessment: insulin resistance and beta-cell function (Diabetologia 1985)
- Gayoso-Diz P et al. — HOMA-IR cut-off values and the metabolic syndrome: EPIRCE study (BMC Endocr Disord 2013)
- Tabák AG et al. — Whitehall II: trajectories of glycaemia and insulin sensitivity before type 2 diabetes (Lancet 2009)
- Crofts C et al. — Identifying hyperinsulinaemia in the absence of impaired glucose tolerance (Diabetes Res Clin Pract 2016)